Common Use

Metaglip is an oral antidiabetic medication used to control blood sugar levels in adults with type 2 diabetes. It combines Glipizide, a sulfonylurea that increases insulin release, and Metformin, a biguanide that decreases liver glucose production and improves insulin sensitivity.

Dosage and Direction

Take Metaglip once or twice daily with meals to reduce gastrointestinal side effects. Follow your doctor's dosage instructions carefully and do not skip doses, even if you feel well.

Precautions

Inform your doctor if you have kidney, liver, or heart disease, or a history of alcohol abuse. Avoid excessive alcohol use while on Metaglip, as it increases the risk of lactic acidosis.

Contraindications

Do not use Metaglip if you have severe kidney dysfunction, metabolic acidosis, or are allergic to Glipizide, Metformin, or other sulfonylureas. It should not be used during episodes of diabetic ketoacidosis.

Possible Side Effects

Common side effects include nausea, diarrhea, dizziness, and headache. Serious but rare risks include lactic acidosis, low blood sugar (especially in elderly patients), or allergic reactions.

Drug Interactions

Tell your doctor about all medications, including NSAIDs, diuretics, steroids, and beta‑blockers, as they may affect blood sugar levels. Avoid contrast dye for imaging procedures while on Metaglip unless advised otherwise.

Missed Dose

If you miss a dose, take it with your next meal unless it's almost time for the next one. Never take two doses at once to compensate for a missed dose.

Overdose

An overdose may cause hypoglycemia or lactic acidosis, which can be life‑threatening. Seek immediate medical attention if symptoms like confusion, rapid breathing, or muscle pain occur.

Storage

Store at room temperature in a dry place, away from heat and direct sunlight. Keep the bottle tightly closed and out of reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self‑treatment and self‑diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self‑treatment.