Common Use

Udenafil is a therapeutic agent designed to improve erectile function by interacting with the phosphodiesterase type 5 (PDE5) enzyme. It has a rapid onset of action, with a T max of 1.0-1.5 hours, and a long duration, with a T 1/2 of 11-13 hours. This makes it suitable for both on-demand and once-daily use. Several studies have demonstrated Udenafil's efficacy and tolerability in these dosing regimens. However, further research is needed to evaluate its effects in diverse ethnic groups and patients with comorbid conditions such as diabetes, hypertension, and benign prostate hyperplasia.

Dosage and Direction

Zudena should be taken orally, regardless of meals. The recommended dose is 100 mg, taken 30 minutes before anticipated sexual activity. The dose can be increased to 200 mg based on individual efficacy and tolerability. The maximum recommended frequency is once per day. Do not break or split the tablet; swallow it whole.

Precautions

Sexual activity may pose risks for patients with cardiovascular disease. Therefore, Udenafil should not be used by men with heart conditions where sexual activity is not advised. Patients with aortic stenosis may be more sensitive to vasodilators, including PDE5 inhibitors. Although prolonged erections (over 4 hours) and priapism (painful erections lasting over 6 hours) are rare, they are potential risks. Immediate medical attention is required if an erection lasts longer than 4 hours. Untreated priapism can lead to irreversible damage to erectile tissue.

Patients who should use Zudena with caution include those with:

• Uncontrolled hypertension (BP>70/100 mmHg) or hypotension (BP<90/50 mmHg)
• Hereditary degenerative retinal diseases (e.g., retinitis pigmentosa, proliferative diabetic retinopathy)
• Recent stroke, myocardial infarction, or coronary artery bypass grafting (within the last 6 months)
• Severe hepatic or renal impairment
• Congenital long QT syndrome or drug-induced QT interval prolongation
• Predisposition to priapism or anatomical penile deformities
• Penile implants
• Cardiovascular conditions such as unstable angina, chronic heart failure (NYHA class II-IV), or uncontrolled arrhythmias

Udenafil is not intended for use in women or individuals under 18 years of age.

Contraindications

Do not use Udenafil with other erectile dysfunction treatments. It is contraindicated in individuals with hypersensitivity to its components or those using nitrates or nitric oxide donors (e.g., nitroglycerin, isosorbide dinitrate, or recreational drugs like amyl nitrate). Combining Udenafil with nitrates can cause a dangerous drop in blood pressure.

Effects on Ability to Drive and Operate Machinery

Patients should understand how Zudena affects them before driving or operating machinery.

Possible Side Effects

Seek emergency medical help if you experience signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Stop using Zudena and seek immediate medical attention if you experience palpitations, prolonged erections, flushing, dizziness, eye pain, increased lacrimation, nasal congestion, or headache. No adverse effects on sperm quality have been reported, and there is no specific research on side effects in men over 71 years of age. If you notice any side effects, contact your doctor or pharmacist.

Drug Interactions

Consult your doctor before taking Udenafil, especially if you are using:

• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, indinavir, cimetidine, erythromycin, grapefruit juice), which may enhance Udenafil's effects
• Dexamethasone, rifampin, or anticonvulsants (e.g., carbamazepine, phenytoin, phenobarbital), which may reduce Udenafil's effectiveness
• Nitroglycerin or alpha-blockers, as they may cause significant blood pressure reduction

Missed Dose

If Zudena is used as needed, you are not likely to be on a dosing schedule. The maximum recommended frequency is once per day.

Overdose

Symptoms of overdose are similar to those at lower doses but occur more frequently. Treatment is symptomatic. Dialysis does not accelerate Udenafil elimination. In case of overdose, seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store Zudena in a dry, dark place at a temperature not exceeding 86°F (30°C). Keep it away from children and pets. Do not store in the bathroom.

Disclaimer

This information provides general guidance about medications and does not cover all directions, possible drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for personalized advice. We are not responsible for any consequences resulting from the use of this information or self-treatment.