Common Use

This medication suppresses the effects of vitamin K, which plays a key role in blood clotting. By inhibiting vitamin K, it helps prevent the formation of blood clots. Blood clots can occur in various parts of the body, including:

• Blood vessels in the extremities after long periods of immobility
• Lung vessels (pulmonary embolism)
• Around artificial heart valves (may cause embolism)

Warfarin is commonly prescribed for:

• Treating blood clots in the lower extremities
• Managing pulmonary embolism
• Preventing stroke in atrial fibrillation
• Preventive therapy after certain orthopedic surgeries (knee or hip replacements)
• Treatment following myocardial infarction

Dosage and Direction

Never take a double dose of Warfarin. The medication can be taken with or without food. Important dosage considerations:

• Patients with liver or kidney impairment may require lower doses
• Always follow your doctor's prescribed dosage schedule

Precautions

While taking Warfarin, observe these precautions:

• Avoid cranberries and cranberry products
• Limit or avoid alcohol consumption
• Be cautious with activities that may cause bruising
• Inform healthcare providers about Warfarin use before any medical procedures
• Regular blood monitoring (INR tests) is essential

Contraindications

Warfarin should not be used in patients with:

• Active bleeding disorders
• Severe liver or kidney failure
• Uncontrolled high blood pressure
• Pregnancy (can cause birth defects)

Possible Side Effects

Common and serious side effects of Warfarin include:

• Bleeding (most serious risk)
• Skin necrosis (rare but dangerous)
• Digestive issues (black tarry stools, nausea)
• Unusual bleeding (nasal, gums)
• Heavy menstrual periods
• Easy bruising
• Hair loss (temporary)

Drug Interactions

Warfarin has numerous potentially dangerous drug interactions. Be especially cautious with:

• Aspirin and other NSAIDs (ibuprofen)
• Acetaminophen (Tylenol)
• Alcohol
• Certain antibiotics
• Many herbal supplements and vitamins
• Cimetidine (Tagamet)

Always inform your doctor about all medications and supplements you're taking.

Missed Dose

If you miss a Warfarin dose:

• Take it as soon as you remember, unless it's almost time for the next dose
• Never take two doses at once
• Do not take extra to make up for a missed dose

Overdose

Symptoms of Warfarin overdose (severe bleeding) include:

• Excessive bleeding from cuts
• Blood in urine or stool
• Unusually heavy menstrual bleeding
• Unexplained bruising

Seek immediate medical attention if overdose is suspected.

Storage

Proper storage of Warfarin:

• Keep at room temperature
• Store in a dry, dark place
• Keep out of reach of children

Disclaimer

This information provides general guidelines about Warfarin but does not replace professional medical advice. Always consult with your healthcare provider about:

• Specific dosage instructions
• Potential drug interactions
• Individual precautions

Do not use this information for self-diagnosis or self-treatment. The publishers are not responsible for any consequences resulting from the use or misuse of this information.