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Common Use
Ursodeoxycholic acid is a bile acid that reduces cholesterol production in the liver and absorption in the intestines. It helps break down cholesterol-based gallstones and improves bile flow in patients with primary biliary cirrhosis.
Primary Uses:
- Treatment of small gallstones in patients who cannot undergo gallbladder surgery.
- Prevention of gallstones in individuals on rapid-weight-loss diets.
- Management of primary biliary cirrhosis.
Note: Ursodeoxycholic acid does not treat calcified gallstones.
Dosage and Direction
Follow your doctor's instructions carefully for dosage. The amount is based on your medical condition and response to treatment.
Important Guidelines:
- Take the medication regularly at the same time each day for optimal results.
- Do not increase the dose without medical advice.
Precautions
Before using Ursodeoxycholic acid, discuss your medical history and current medications with your doctor.
Key Considerations:
- Avoid if allergic to ursodiol or other bile acids.
- Not recommended for certain liver, gallbladder, or bile duct disorders.
- May cause dizziness, avoid driving or operating machinery if affected.
- Limit alcohol consumption.
- Use during pregnancy or breastfeeding only under medical supervision.
Contraindications
Ursodeoxycholic acid is not suitable for:
- Calcified cholesterol stones, radiopaque stones, or bile pigment stones.
- Conditions requiring gallbladder removal (e.g., cholecystitis, pancreatitis, biliary obstruction).
- Patients with a known allergy to bile acids.
Possible Side Effects
Most users do not experience serious side effects, but potential reactions include:
Common Effects:
- Stomach upset, nausea, diarrhea, dizziness, back pain, hair loss, or cough.
Serious Effects (Seek medical help if observed):
- Weakness, swelling in ankles/feet, increased thirst/urination, fever, persistent sore throat.
- Severe allergic reactions (rash, itching, swelling of face/tongue/throat, trouble breathing).
Drug Interactions
Ursodeoxycholic acid may interact with other medications, altering their effects.
Key Interactions:
- Aluminum-based antacids
- Cholesterol-lowering drugs (cholestyramine, clofibrate, colestipol)
- Estrogens and oral contraceptives
Consult your doctor before starting, stopping, or adjusting any medications.
Missed Dose
If you miss a dose, take it as soon as you remember. If it's near the next dose time, skip the missed dose.
Overdose
In case of suspected overdose, contact poison control or seek emergency medical help immediately. Do not take extra doses.
Storage
Store at room temperature in a tightly closed container.
Disclaimer
This information is not a substitute for professional medical advice. Always consult your healthcare provider before starting or changing treatment. We do not guarantee the accuracy of this content and disclaim liability for any consequences of self-treatment.