Common Use

Trihexyphenidyl is used to treat symptoms of Parkinson's disease. It may be prescribed alone or in combination with other medications. This medication helps control:

• Rigidity
• Drooling
• Tremors
• Other Parkinson's disease symptoms

It may also be prescribed to prevent similar symptoms caused by certain medications including:

• Chlorpromazine (Thorazine)
• Fluphenazine (Prolixin)
• Perphenazine (Trilafon)

Dosage and Directions

Artane should be used only by the patient for whom it has been prescribed. Follow your doctor's instructions carefully regarding dosage and frequency.

• Take the exact amount prescribed - no more or less
• Dosage depends on your specific condition
• Typically taken 3-4 times daily with food and at bedtime
• Controlled-release versions are usually taken every 12 hours

Precautions

Before taking Artane, discuss the following with your doctor:

• Any history of liver or kidney disease
• Potential dizziness or lightheadedness
• The need to avoid alcohol and other medications

Additional precautions include:

• Avoid driving or hazardous activities until you know how Artane affects you
• Do not consume grapefruit or grapefruit juice while taking Artane
• Maintain good dental hygiene - brush, floss, and see your dentist regularly
• Contact your doctor if symptoms persist or worsen

Contraindications

Special dosage adjustments or avoidance may be necessary if you have:

• Liver or kidney infection
• Gastrointestinal problems

Possible Side Effects

Serious side effects that require immediate medical attention:

• Severe neutropenia (low white blood cells)
• Gastrointestinal or cerebral hemorrhage
• Thrombotic thrombocytopenic purpura (TTP)
• Severe headache
• Indigestion
• Flushing

Drug Interactions

Artane may interact with:

• Phenytoin (Dilantin)
• Tamoxifen (Nolvadex)
• Tolbutamide (Orinase)
• Torsemide (Demadex)
• Fluvastatin (Lescol)
• Blood thinners like warfarin, heparin, and related medications

Always discuss all medications with your doctor before starting Artane.

Missed Dose

If you miss a dose:

• Take it as soon as you remember
• If close to the next dose, skip the missed one
• Never take a double dose to compensate

Overdose

If you suspect an overdose:

• Seek immediate medical attention
• Specific overdose symptoms are not well documented

Storage

Proper storage instructions:

• Store at 59-86°F (15-30°C)
• Keep away from heat, moisture, and light
• Store safely out of children's reach

Disclaimer

This information provides general guidelines about Artane but does not include all possible details about directions, drug interactions, or precautions. Never use this information for self-diagnosis or self-treatment. Always consult with your healthcare provider for specific medical advice relevant to your situation. The reliability of this information cannot be guaranteed, and we are not responsible for any consequences resulting from its use.