Common Use

Imipramine belongs to the class of tricyclic antidepressants (TCAs). This medication is used to treat major depression, panic disorder, and enuresis (inability to control urination). Imipramine can also be applied for other purposes.

Dosage and Direction

Take Tofranil by mouth with a glass of water, with or without food. Take the drug only as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing, or chewing this medicine.

Do not take the medicine more often than prescribed. Do not stop taking it except on the advice of your doctor.

It may take time for the medicine to work. Consult your doctor concerning the proper dose for you.

Precautions

Before taking Imipramine, tell your doctor or pharmacist if you are allergic to it or have other allergies.

Inform your doctor or pharmacist if you have bipolar disorder, confusion, or eye, liver, or kidney problems.

Avoid drinking alcohol and smoking while being treated with this medication.

Older adults may be more sensitive to the side effects of the medicine.

During pregnancy, this treatment should be used only when absolutely necessary.

As this medication can be absorbed through the skin, women who are pregnant or may become pregnant should not handle it.

Contraindications

Tofranil should not be used by pregnant or nursing women, children, or patients who have demonstrated hypersensitivity to Imipramine.

Possible Side Effects

The most common side effects include dizziness, drowsiness, lightheadedness, confusion, agitation, and increased anxiety.

A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects.

Talk to your doctor or pharmacist for more details. If you notice effects not listed here, contact your doctor or pharmacist.

Drug Interaction

Tell your doctor or pharmacist about all prescription and nonprescription/herbal products you have used before taking this medication.

Imipramine can interact with:

• MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide, Tranylcypromine, etc.
• Anti-arrhythmic medications: Propafenone, Quinidine, etc.
• Selective Serotonin Reuptake Inhibitors (SSRIs): Citalopram, Dapoxetine, Fluoxetine, Fluvoxamine, Paroxetine, etc.
• Antipsychotics: Fluphenazine, etc.
• H2-receptor antagonists: Cimetidine, Ranitidine, Famotidine, Nizatidine.

Consult your doctor or pharmacist for more details.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take a double dose.

Overdose

If you suspect an overdose, seek emergency medical attention immediately. Symptoms may include chest pain, nausea, irregular heartbeat, and lightheadedness or fainting.

Storage

Store the medication at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store it in the bathroom. Keep all drugs out of reach of children and pets.

Disclaimer

We provide only general information about medications, which does not cover all directions, possible drug interactions, or precautions. The information on this site cannot be used for self-treatment or self-diagnosis. Any specific instructions for a particular patient should be agreed upon with a healthcare provider or doctor. We disclaim reliability of this information and any mistakes it may contain. We are not responsible for any direct, indirect, special, or other damages resulting from the use of this information or the consequences of self-treatment.