Common Use

Symmetrel is an antiviral medication used to prevent or treat certain influenza infections. It works by blocking the actions of viruses in the body. Additionally, Symmetrel is prescribed for treating Parkinson's disease and "Parkinson-like" symptoms, such as stiffness and shaking.

Dosage and Direction

Take Symmetrel orally with a full glass of water or with food/milk. Swallow the tablet whole; do not crush it. For optimal results, use Symmetrel at the same time each day. The usual dosage ranges from 100 to 200 mg daily, depending on body weight. The recommended adult dose varies based on the condition being treated:

• Treatment of Parkinson's Disease: Start with 100 mg once daily. After one to several weeks, the dose may increase to 100 mg twice daily.
• Treatment and Prevention of Influenza A Infections: Adults and children aged 13 and older should take 200 mg daily. Children aged 9-12 should take 100 mg twice daily. For children aged 1 to 12, the dose is determined by body weight.
• Prevention of Influenza A Infections: Symmetrel should be taken before or after contact with an infected person and continued for 10 days after exposure.

Note: This information is for review purposes only. Always consult your doctor before using Symmetrel to ensure the best results.

Precautions

Symmetrel has been associated with suicide attempts and deaths, even in patients without a history of psychiatric illness. It may worsen symptoms in individuals with psychiatric disorders or substance abuse. Patients with a history of epilepsy, congestive heart failure, peripheral edema, eczematoid rash, or renal impairment should be closely monitored. Avoid use in patients with untreated angle-closure glaucoma. Discontinuation or dose reduction should be supervised, as cases of Neuroleptic Malignant Syndrome (NMS) have been reported. NMS is a life-threatening condition characterized by fever, muscle rigidity, altered consciousness, and other symptoms. Avoid alcohol during treatment. Symmetrel should not be used during pregnancy, breastfeeding, or by individuals planning to become pregnant without medical advice.

Contraindications

Symmetrel is contraindicated in individuals hypersensitive to its components, those prone to convulsions, or with a history of gastric ulceration or severe renal disease. It is also contraindicated during pregnancy.

Possible Side Effects

Possible side effects of Symmetrel include allergic reactions and the following symptoms:

• Shortness of breath, even with mild exertion
• Swelling, rapid weight gain
• Depression, agitation, or aggression
• Behavioral changes, hallucinations, or suicidal thoughts
• Decreased urination
• High fever, stiff muscles, confusion, rapid heartbeat, or fainting
• Restless muscle movements in the eyes, tongue, jaw, or neck
• Uncontrolled shaking (tremor)

Less serious side effects may include:

• Dizziness, drowsiness, headache
• Insomnia, strange dreams
• Nervousness
• Nausea, diarrhea, constipation, loss of appetite
• Dry mouth or dry nose
• Loss of balance or coordination

If you experience any of these side effects, stop using Symmetrel and consult your doctor immediately. Report any unusual symptoms to your healthcare provider.

Drug Interaction

Symmetrel may interact with the following drugs:

• Atropine, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, methscopolamine, propantheline, scopolamine
• Quinine, quinidine
• Diuretics such as triamterene, hydrochlorothiazide
• Phenothiazines such as prochlorperazine, thioridazine

Drug interactions do not always require discontinuing a medication, but they may alter drug effectiveness. Consult your doctor to manage interactions appropriately.

Missed Dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose. Resume your regular dosing schedule the next day.

Overdose

Overdosing on Symmetrel can be fatal. Symptoms may include fever, anxiety, severe headache, confusion, hallucinations, agitation, aggression, personality changes, tremor, balance issues, rapid heartbeat, decreased urination, trouble breathing, seizures, or fainting. Seek immediate medical attention if overdose symptoms occur.

Storage

Store Symmetrel at room temperature (59-77°F or 15-25°C), away from light, moisture, children, and pets. Do not use after the expiration date.

Disclaimer

This information provides a general overview of Symmetrel and does not cover all directions, possible drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for personalized advice. We disclaim responsibility for any errors or damages resulting from the use of this information or self-treatment practices.