Common Use

Sporanox is an azole antifungal medication used to treat serious fungal infections such as blastomycosis, histoplasmosis, and aspergillosis. It works by killing sensitive fungi through interference with the fungal cell membrane formation. Sporanox is also prescribed for onychomycosis, which affects the toenails and fingernails.

Dosage and Direction

Take Sporanox orally with or without food or milk. For optimal results, take it at the same time each day. Dosage varies depending on the type of infection:

1. Treatment of Blastomycosis and Histoplasmosis

• Adults: 200 mg once daily. Do not exceed 400 mg daily.
• Children: Consult a doctor for appropriate dosage.

2. Treatment of Aspergillosis

• Adults: 200 to 400 mg daily.
• Children: Consult a doctor for appropriate dosage.

3. Treatment in Life-Threatening Situations

• Adults: 200 mg three times daily (600 mg/day) for the first 3 days. Continue treatment for more than three months or until clinical and laboratory tests confirm the infection has subsided.
• Children: Consult a doctor for appropriate dosage.

4. Treatment of Onychomycosis (Toenails with or without Fingernail Involvement)

• Adults: 200 mg once daily for 12 consecutive weeks.
• Children: Consult a doctor for appropriate dosage.

5. Treatment of Onychomycosis (Fingernails Only)

• Adults: 200 mg twice daily for 1 week, repeated after a 3-week break.
• Children: Consult a doctor for appropriate dosage.

Note: This information is for review only. Always consult your doctor before use to ensure the best results.

Precautions

Sporanox may negatively affect the heart and should not be used for fungal nail infections if you have a history of cardiac issues like congestive heart failure. Inform your doctor if you have conditions such as heart rhythm disorders, kidney or liver disease, breathing disorders, cystic fibrosis, or Long QT syndrome. Avoid antacids within 1 hour before or 2 hours after taking Sporanox. Do not use Sporanox during pregnancy, while planning pregnancy, or while breastfeeding without medical advice.

Contraindications

Sporanox is contraindicated for individuals hypersensitive to itraconazole or similar medications like fluconazole or ketoconazole, or those with a history of congestive heart failure.

Possible Side Effects

Side effects may include allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), fever, shortness of breath, swelling, rapid weight gain, hearing problems, numbness, pain during urination, nausea, stomach pain, dark urine, clay-colored stools, or jaundice. Less serious side effects include diarrhea, constipation, mild stomach pain, itching, skin rash, headache, dizziness, or cold symptoms. Discontinue use and consult your doctor if any unusual symptoms occur.

Drug Interactions

Sporanox may interact with drugs such as cisapride, dihydroergotamine, dofetilide, ergonovine, ergotamine, lovastatin, methylergonovine, midazolam, nisoldipine, pimozide, quinidine, simvastatin, or triazolam. Drug interactions do not always require discontinuing medication but should be managed under medical supervision.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose. Resume your regular dosing schedule the next day.

Overdose

Symptoms of Sporanox overdose are not well-documented. Seek immediate medical attention if you experience any unusual symptoms.

Storage

Store Sporanox at room temperature (59-77°F or 15-25°C) away from light, moisture, children, and pets. Do not use after the expiration date.

Disclaimer

This information provides a general overview of Sporanox and does not cover all instructions, drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific guidance. We disclaim liability for any inaccuracies or consequences of self-treatment.