Common Use

Spiriva is a long-acting muscarinic receptor antagonist. It works by reversibly blocking M3 receptors in the respiratory tract, leading to relaxation of the smooth muscles in the bronchial tree. Due to its high receptor affinity and slow release from the M3 receptor complex, Spiriva provides prolonged local action. Its bronchodilatory effect is dose-dependent and lasts for at least 24 hours. This medication is used to treat bronchial spasms (wheezing) associated with chronic obstructive pulmonary disease (COPD), chronic bronchitis, and emphysema.

Dosage and Direction

Spiriva is available as capsules containing powder for inhalation, used with the HandiHaler device. It should be taken at the same time each day for optimal results.

Precautions

• Use with caution in patients with narrow-angle glaucoma, urination disorders due to prostatic hypertrophy, or bladder neck obstruction.
• Spiriva is not intended for immediate relief of bronchial spasms.
• Avoid contact with the eyes.
• Regular monitoring is required for patients with moderate to severe renal failure or those taking medications excreted by the kidneys.
• Inhaled medications may cause paradoxical bronchospasm or similar reactions.
• Avoid use during pregnancy or breastfeeding.

Contraindications

• Spiriva should not be used by patients with hypersensitivity to the drug, atropine, or its derivatives (ipratropium, oxytropine).
• Safety and efficacy in adolescents under 18 years of age have not been established.

Possible Side Effects

• Common side effects include dry mouth, throat pain, coughing, and paradoxical bronchospasm.
• If the medication enters the eyes, it may cause changes in accommodation.
• Allergic reactions such as rash or swelling may occur.
• Rare side effects include rapid heartbeat, acute glaucoma, difficulty urinating in men with prostatic hypertrophy, and constipation.

Drug Interactions

Concurrent use of Spiriva with other anticholinergic medications is not recommended.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose. Take your medication at the same time daily to avoid missing a dose.

Overdose

No cases of overdose have been reported when Spiriva is used at therapeutic doses. Excessive doses may lead to anticholinergic effects such as changes in accommodation and dry mouth. Acute poisoning is unlikely due to the low bioavailability of the inhaled medication.

Storage

Store Spiriva at room temperature, away from moisture, sunlight, children, and pets. Keep it in a tightly sealed container.

Disclaimer

This information is provided for general purposes only and does not cover all possible uses, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider for personalized advice. We do not guarantee the accuracy or reliability of this information and are not liable for any damages resulting from its use or consequences of self-treatment.