Common Use

Sibelium is a calcium channel blocker used for:

• Preventing classic or common migraine (with or without aura)
• Symptomatic treatment of vestibular vertigo

Each capsule typically contains 5.9 mg of flunarizine hydrochloride.

Dosage and Direction

• Adults: 10 mg (two 5 mg capsules) at night
• Patients over 65: Reduce to 5 mg daily

Discontinue use if depressive symptoms, extrapyramidal symptoms, or other unacceptable side effects occur, or if no significant improvement is observed after 2 months. For satisfactory responses, maintenance therapy involves taking the medication for 5 days followed by 2 medicine-free days each week.

Precautions

• Sibelium often causes drowsiness
• Enhances effects of alcohol and CNS depressants
• Alcohol consumption should be avoided during treatment
• Use caution when driving or performing tasks requiring concentration

Contraindications

• Hypersensitivity to flunarizine
• History of depressive illness
• Pre-existing extrapyramidal disorders
• Pregnancy and breastfeeding

Possible Side Effects

Common side effects:

• Drowsiness
• Fatigue
• Weight gain
• Increased appetite
• Agitation
• Sedation
• Tachycardia

Less common side effects:

• Digestive issues: heartburn, gastralgia, nausea
• Neurological symptoms: insomnia, anxiety
• Other: muscle ache, dry mouth, skin rash, galactorrhoea

Long-term use may cause depression (especially in women) and extrapyramidal symptoms (more frequent in elderly patients).

Drug Interactions

• Hepatic enzyme inducers (carbamazepine, phenytoin) may decrease Sibelium blood levels
• May cause galactorrhoea in women taking oral contraceptives

Missed Dose

Contact your doctor if you miss a dose. Never double the dose to make up for a missed one.

Overdose

Symptoms may include sedation, agitation, and tachycardia. Seek immediate medical attention if overdose is suspected.

Storage

• Store at room temperature (below 25°C/77°F)
• Keep out of reach of children and pets

Disclaimer

This information provides general guidelines about Sibelium and does not replace professional medical advice. Always consult your healthcare provider for personalized recommendations. We are not liable for any consequences resulting from self-treatment based on this information.