Common Use

Serophene is a non-steroid anti-estrogen medication. Its mechanism of action involves binding specifically to estrogen receptors in the ovary and pituitary gland. In patients with low estrogen levels, it produces an estrogenic effect, while in those with high estrogen levels, it acts as an anti-estrogen. Small doses increase the secretion of gonadotropins, such as prolactin, follicle-stimulating hormone (FSH), and interstitial cell-stimulating hormone, promoting ovulation. In larger doses, it inhibits gonadotropin secretion. Overall, Serophene stimulates ovulation and prepares the body for pregnancy. It is also used to treat male infertility caused by low sperm production.

Dosage and Direction

Serophene is typically taken to stimulate ovulation at a dosage of 50 mg once daily at bedtime, starting on the 5th day of the menstrual cycle for 5 days. If no ovulation occurs within 30 days, the dose may be increased to 150 mg daily or the course extended to 10 days. Always follow your doctor's instructions and do not exceed the prescribed dosage.

Precautions

Before taking Serophene, inform your doctor if you have a history of allergic reactions to clomiphene, liver disease, mental depression, or thrombophlebitis. This medication may cause vision problems, dizziness, or lightheadedness. Exercise caution when driving or operating machinery that requires focus.

Contraindications

• Hypersensitivity to the drug
• Liver or kidney failure
• Metrorrhagia of unknown origin
• Ovarian cysts
• Neoplasms of the genital organs
• Hypofunction or tumors of the pituitary gland
• Endometriosis
• Ovarian failure with hyperprolactinemia
• Pregnancy

Possible Side Effects

• Allergic reactions such as swelling of the lips, tongue, or face, or hives
• Ovarian enlargement causing abdominal or pelvic pain
• Flushing, nausea, vomiting, or diarrhea
• Blurred vision
• Headache
• Abnormal uterine bleeding

Drug Interaction

Inform your doctor and laboratory staff about all medications and herbal products you are taking while on Serophene treatment.

Missed Dose

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. Do not double the dose to make up for a missed one.

Overdose

Seek immediate medical attention if you suspect an overdose of Serophene.

Storage

Store Serophene in a dry place away from sunlight at room temperature, between 15-30°C (59-86°F).

Disclaimer

The information provided here is general and does not cover all possible directions, drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions tailored to your condition. We are not responsible for any errors in the information or any consequences resulting from its use or self-treatment.