Common use

Ropinirole is a dopamine agonist used to treat symptoms of Parkinson's disease and moderate to severe Restless Legs Syndrome (RLS). It works by stimulating dopamine receptors in the brain, helping to improve movement control and reduce muscle stiffness, tremors, or restlessness. In Parkinson's, it can be used alone or in combination with other medications like levodopa. In RLS, it helps relieve uncomfortable leg sensations that disrupt sleep.

Dosage and direction

For Parkinson's disease, ropinirole is usually started at a low dose (e.g., 0.25 mg three times a day) and gradually increased to minimize side effects. For RLS, the standard dose is taken once daily 1-3 hours before bedtime. It can be taken with or without food, but taking it with food may reduce nausea. Follow your doctor's instructions exactly and do not change the dose without medical guidance.

Precautions

• Tell your doctor if you have a history of heart disease, low blood pressure, sleep disorders, or mental health conditions
• Ropinirole may cause sudden drowsiness or sleep attacks, even during activities like driving
• It can cause dizziness when standing up quickly, especially at the start of treatment
• Patients should avoid alcohol and be monitored for changes in behavior or mood

Contraindications

• Allergy to ropinirole or any of its ingredients
• Severe cardiovascular conditions
• History of compulsive behaviors
• Not recommended during pregnancy or breastfeeding without medical approval
• Pediatric use requires specialist evaluation

Possible side effects

• Common: Nausea, dizziness, fatigue, low blood pressure
• Less common: Drowsiness, hallucinations
• Rare but serious: Fainting, irregular heartbeat, severe mental changes, compulsive behaviors
• Report any unusual symptoms to your doctor immediately

Drug interactions

• Medications that affect dopamine levels
• Drugs that impact CYP1A2 liver enzymes (e.g., ciprofloxacin, fluvoxamine)
• Antipsychotics may reduce effectiveness
• Sedatives and alcohol may increase side effects
• Always provide your full medication list to your doctor

Missed dose

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double the dose. For extended-release forms, take the missed dose the next day at the regular time. Contact your doctor if you frequently forget doses.

Overdose

• Symptoms may include severe nausea, vomiting, tremors, confusion
• Potential hallucinations, fainting, or cardiac issues
• Seek immediate medical help for suspected overdose
• Hospital treatment typically involves supportive care

Storage

• Store at room temperature (20°C to 25°C or 68°F to 77°F)
• Protect from moisture and heat
• Keep in original container, tightly closed
• Do not store in bathroom or near sink
• Keep out of reach of children and pets

Disclaimer

This information provides general knowledge about medications and does not cover all directions, possible drug interactions, or precautions. Never use this information for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions regarding your treatment. We do not guarantee the accuracy or completeness of this information and disclaim any liability for damages resulting from its use.