Common Use

Ranitidine is an H2 (histamine-2) receptor antagonist used to reduce stomach acid production. It is prescribed to treat:

• Gastric and duodenal ulcers
• Gastroesophageal reflux disease (GERD)
• Zollinger-Ellison syndrome
• Heartburn

It works by blocking histamine receptors in the stomach lining, thereby decreasing acid secretion.

Dosage and Direction

Ranitidine is available in:

• Tablets
• Capsules
• Injectable forms

Typical adult oral doses:

• 150 mg twice daily
• 300 mg once daily at bedtime

Dosage depends on the condition being treated. It can be taken with or without food but should be taken with water and at regular intervals for best results.

Precautions

Before using ranitidine, inform your doctor if you have:

• Kidney or liver problems
• Porphyria
• History of acute allergic reactions

Special considerations:

• Use with caution in older adults
• Monitor long-term users for potential risks
• Avoid alcohol and NSAIDs as they may worsen gastric irritation

Contraindications

Ranitidine should not be used in:

• People with known allergy to H2 blockers
• Patients with history of QT prolongation without medical supervision

Special cases requiring medical evaluation:

• Pregnant women
• Breastfeeding mothers

Possible Side Effects

Common side effects include:

• Headache
• Constipation
• Diarrhea
• Fatigue

Rare side effects include:

• Liver dysfunction
• Bradycardia
• Skin rashes
• Confusion in elderly patients

Note: Long-term use may alter vitamin B12 absorption.

Drug Interaction

Ranitidine may interact with:

• Reduce absorption of medications requiring acidic environment (ketoconazole, itraconazole)
• Warfarin
• Glipizide
• Midazolam

Important: Always tell your doctor about all medications and supplements you are using.

Missed Dose

If you miss a dose:

1. Take it as soon as you remember
2. If it's almost time for the next dose, skip the missed one
3. Do not double the dose

Overdose

Overdose symptoms may include:

• Unusual tiredness
• Vomiting
• Rapid heartbeat
• Difficulty breathing

Important: Seek emergency medical help in case of suspected overdose.

Storage

Proper storage instructions:

• Store at room temperature
• Keep away from light and moisture
• Do not store in the bathroom
• Keep out of reach of children

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis.

Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain.

We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.