Common Use

Prednisolone is a synthetic version of the hormones cortisone and hydrocortisone. It has strong anti-inflammatory, antiallergic, antishock, and detoxifying effects. It works by binding to glucocorticosteroid receptors in cells, which helps reduce inflammation by blocking certain chemicals involved in the inflammatory process. It can also decrease the production of substances that trigger allergic reactions. Prednisolone is used to treat a wide range of conditions including allergies, skin disorders, arthritis, psoriasis, lupus, asthma, leukemia, eczema, and adrenal gland issues.

Dosage and Direction

The dosage of Prednisolone varies depending on the condition being treated. For acute conditions, the initial dose is typically 5-60 mg per day, while the maintenance dose is usually 5-10 mg per day. Always follow your doctor's instructions and do not exceed the prescribed dose.

Precautions

Before using Prednisolone, inform your doctor about any existing health conditions, especially liver or kidney disease, thyroid disorders, diabetes, tuberculosis, or mental health issues. This medication can weaken the immune system, making you more susceptible to infections. Avoid contact with people who have contagious illnesses like chickenpox or measles. Do not stop taking Prednisolone suddenly, as this can cause withdrawal symptoms. Pregnant women should consult their doctor before using this medication.

Contraindications

Prednisolone should not be used by patients with severe hypertension, diabetes, Itsenko-Cushing syndrome, or circulatory failure. It is also contraindicated in pregnant women, patients with acute endocarditis, psychosis, nephritis, osteoporosis, stomach ulcers, or active tuberculosis. Elderly patients should use this medication with caution.

Side Effects

Possible side effects of Prednisolone include weight gain, excess hair growth, acne, menstrual irregularities, osteoporosis, stomach ulcers, high blood sugar, and mental health issues. Long-term use may lead to more severe conditions like Itsenko-Cushing syndrome or thinning skin. If you experience vision changes, severe depression, or unusual bleeding, contact your doctor immediately.

Drug Interaction

Prednisolone may interact with anti-diabetic or anticoagulant medications, requiring dose adjustments. Patients with Addison disease should use caution when combining Prednisolone with barbiturates.

Missed Dose

If you miss a dose of Prednisolone, contact your doctor or healthcare provider for guidance. Do not double the dose to make up for a missed one.

Overdose

While an overdose of Prednisolone is unlikely to be life-threatening, prolonged use can lead to complications such as thinning skin, easy bruising, or changes in body fat distribution. Seek medical advice if you experience these symptoms.

Storage

Store Prednisolone at room temperature, ideally between 20-25°C (68-77°F). Keep it away from moisture, heat, and sunlight. Do not store it in the bathroom or in areas accessible to children.

Disclaimer

The information provided here is for general purposes only and does not cover all possible uses, interactions, or precautions. Always consult your healthcare provider for personalized advice. Do not use this information for self-diagnosis or self-treatment. We are not responsible for any consequences resulting from the use of this information.