Common Use

Pletal is a medication used for reducing attacks of intermittent claudication. This condition causes pain, cramping, numbness, or weakness in the foot, hip, thigh, or buttocks that may occur after walking.

Pletal is a phosphodiesterase type 3 inhibitor. It works by:

• Widening arteries that supply blood to the legs
• Decreasing the ability of platelets to stick together

Dosage and Directions

Take Pletal exactly as directed by your doctor. Follow these instructions:

• Take by mouth at least 30 minutes before or 2 hours after eating
• Avoid grapefruit or grapefruit juice while taking Pletal
• Effects are not immediate - benefits may be noticed in 2 to 4 weeks
• Full effects may take up to 12 weeks

Precautions

Before taking Pletal, discuss with your doctor if you:

• Are pregnant, planning pregnancy, or breast-feeding
• Are taking any prescription, nonprescription, herbal, or dietary supplements
• Have allergies to medicines or foods
• Have liver or kidney problems

Contraindications

Do not use Pletal if you have:

• Allergy to any component of the medication
• Heart failure

Possible Side Effects

Common side effects may include:

• Abnormal stools
• Back pain
• Swelling of ankles, feet, or hands
• Diarrhea
• Dizziness
• Headache
• Nausea

Serious side effects require immediate medical attention:

• Allergic reactions (rash, difficulty breathing, swelling)
• Black, tarry stools
• Irregular heartbeat
• Unusual bruising or bleeding

Drug Interactions

These medications may interact with Pletal:

• Ketoconazole
• Erythromycin
• Diltiazem
• Omeprazole

Missed Dose

If you miss a dose of Pletal:

• Take it as soon as possible
• If close to next dose, skip the missed dose
• Never take double doses
• Contact your healthcare provider if multiple doses are missed

Overdose

Seek emergency medical help for overdose symptoms:

• Severe diarrhea or dizziness
• Irregular heartbeat
• Extreme fatigue
• Low blood pressure

Storage

Store Pletal properly:

• Keep between 59-86°F (15-30°C)
• Store in a tightly closed container
• Avoid heat, moisture, and light
• Keep away from children and pets

Disclaimer

This information provides a general overview about Pletal and does not include all possible details. Always consult your healthcare provider for personalized medical advice. Proper diagnosis and treatment should come from qualified medical professionals. This content is not responsible for any health decisions made without professional consultation.