Common Use

Nimotop is a nimodipine-based medication effective in preventing or relieving vessel spasms caused by substances like serotonin or histamine. Thanks to its high lipophilicity, it can cross the blood-brain barrier (BBB). Nimotop enhances neuronal stability and function, positively impacting learning and memory by blocking Ca2+ channels in critical brain regions such as the hippocampus and cerebral cortex.

Dosage and Direction

Take Nimotop orally as prescribed. Do not exceed the recommended dose. Consume it on an empty stomach with a full glass of water, either one hour before or two hours after a meal. For optimal results, take it regularly as directed.

Precautions

• Exercise caution if you have severe bradycardia, liver failure, mild to moderate hypotension, left ventricular failure, intracranial hypertension, or brain tissue edema.
• Avoid grapefruit juice while on Nimptop.
• Using Nimotop with rifampicin may reduce its effectiveness.
• Concurrent use with cimetidine or valproic acid may increase nimodipine blood serum levels.
• Combining Nimotop with beta-blockers can cause a significant drop in blood pressure.
• Using Nimotop with procainamide or quinidine may increase the risk of QT interval elongation.

Contraindications

Do not use Nimotop if you have hypersensitivity to the medication, severe hypotension, or are pregnant or breastfeeding.

Possible Side Effects

• Seek immediate medical attention for severe allergic reactions, such as skin rash, difficulty breathing, facial swelling, or hives.
• Contact your doctor if you experience fainting, severe dizziness, unusual heart rate, easy bruising or bleeding, weakness, or swelling in your legs or ankles.

Drug Interactions

• Inform your doctor about all medications, herbal products, and supplements you are using.
• Fluoxetine can increase nimodipine serum levels.
• Long-term use of nortriptyline with nimodipine may slightly increase nimodipine levels.
• Phenobarbital, phenytoin, or carbamazepine may reduce nimodipine bioavailability if used before starting nimodipine.

Missed Dose

If you miss a dose, take it as soon as you remember. However, skip it if it is almost time for your next dose.

Overdose

Seek immediate medical attention if you experience symptoms like chest pain, dizziness, fainting, weakness, shortness of breath, unusual heart rate, confusion, slurred speech, or coma.

Storage

Store Nimotop in a dry, tightly sealed container away from sunlight at room temperature (15-30°C or 59-86°F). Keep it out of reach of children and pets.

Disclaimer

This information is general and does not cover all directions, drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions. We are not responsible for any errors or consequences arising from the use of this information or self-treatment.