Common Use

Lopid is a fibric acid derivative similar to fenofibrate (Tricor). It works by reducing triglycerides and increasing high-density lipoprotein (HDL) cholesterol, thereby lowering the risk of atherosclerosis, stroke, and heart attack. While its exact mechanism is not fully understood, Lopid is particularly effective in treating high cholesterol and triglyceride levels in patients with pancreatitis.

Dosage and Direction

The recommended dosage is 600 mg taken twice daily, 30 minutes before breakfast and dinner.

Precautions

• Follow your doctor's guidance on diet, exercise, and weight management, as Lopid is only part of the treatment plan.
• Avoid foods high in cholesterol and fats.
• Regularly monitor blood fat levels.
• Your doctor may require periodic kidney or liver function tests.
• Inform your doctor if you have liver disease, gallbladder disease, or severe kidney disease.

Contraindications

Lopid should not be used by individuals with an allergy to gemfibrozil, liver disease, gallbladder disease, severe kidney disease, or those taking repaglinide (Prandin).

Possible Side Effects

Seek immediate medical attention if you experience sharp stomach pain, jaundice, blurred vision, painful urination, eye pain, or see halos around lights after taking Lopid or eating.

Drug Interactions

• Increased risk of rhabdomyolysis (muscle injury) when used with statins like pravastatin (Pravachol), lovastatin (Mevacor), rosuvastatin (Crestor), simvastatin (Zocor), fluvastatin (Lescol), or atorvastatin (Lipitor). Severe cases may cause kidney damage or death.
• Concurrent use with warfarin increases bleeding risk, requiring dose adjustments.
• Lopid increases blood levels of repaglinide (Prandin) in diabetic patients.
• Cholestyramine (Questran) and colestipol (Colestid) reduce Lopid's effectiveness. Take Lopid 1 hour before or 4-6 hours after these medications.

Missed Dose

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double the dose. Resume your regular schedule the next day.

Overdose

Symptoms of overdose include nausea, diarrhea, vomiting, stomach cramps, and joint or muscle pain. Seek immediate medical help if these occur.

Storage

Store Lopid at room temperature, between 20-25°C (68-77°F).

Disclaimer

This information provides a general overview of Lopid and does not cover all directions, possible interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider for specific instructions. We disclaim responsibility for the accuracy of this information and any consequences of its use.