Common Use

Lisinopril is a medication used to treat high blood pressure (hypertension) in adults and children aged 6 and older. It is also prescribed for conditions such as renovascular hypertension, acute myocardial infarction in clinically stable patients, heart failure (as an adjuvant treatment), and diabetic nephropathy. By relaxing and expanding blood vessels, Lisinopril helps prevent strokes, heart attacks, and kidney problems. Additionally, it is used in the recovery phase after acute myocardial infarction and is often combined with other medications, such as diuretics or digoxin, to manage heart failure. Lisinopril belongs to the class of drugs known as ACE inhibitors.

Dosage and Direction

Lisinopril is typically taken once daily by adults. The dosage is personalized based on the patient's condition, kidney function, and concurrent therapies. The usual starting dose is 2.5-5 mg, with an average maintenance dose of 5-20 mg. The maximum daily dose should not exceed 80 mg.

Precautions

Treatment with Lisinopril requires regular medical supervision, including monitoring of water-electrolyte balance. Blood pressure, protein levels, plasma potassium, urea nitrogen, creatinine, renal function, blood count, body weight, and dietary habits should be closely observed. Caution is advised during surgical procedures, including dental surgery, particularly when using general anesthetics that may lower blood pressure.

Contraindications

Lisinopril should not be used by individuals with hypersensitivity to the drug, pregnant women, or those who are breastfeeding.

Possible Side Effects

• Headache
• Dizziness
• Nervousness
• Fainting
• Drowsiness
• Insomnia
• Tremors
• Convulsions
• Visual disturbances
• Palpitations
• Chest pain
• Hypotension
• Arrhythmia
• Dry cough
• Malignant lung tumors
• Hemoptysis
• Pain when breathing
• Bronchitis
• Dry mouth
• Indigestion
• Heartburn
• Vomiting
• Diarrhea or constipation
• Bloating
• Abdominal pain
• Renal failure
• Weakened libido
• Impotence
• Arthritis
• Neck or back pain
• Rash
• Urticaria
• Stevens-Johnson syndrome

Drug Interactions

Lisinopril may interact with the following medications:

• Gold injections for arthritis
• Lithium (Lithobid, Eskalith)
• Potassium supplements (e.g., K-Dur, Klor-Con)
• Salt substitutes containing potassium
• Insulin or oral diabetes medications
• Aspirin or NSAIDs (e.g., ibuprofen, diclofenac, naproxen)
• Diuretics (water pills)

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra medicine to make up for the missed dose.

Overdose

Seek emergency medical help immediately if you suspect an overdose. Symptoms of Lisinopril overdose may include extreme dizziness, light-headedness, or fainting.

Storage

Store Lisinopril at room temperature, away from moisture and heat.

Disclaimer

This information provides a general overview of Lisinopril and does not cover all possible uses, directions, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider or doctor for specific medical advice. We disclaim any responsibility for the reliability of this information or any errors it may contain. We are not liable for any direct, indirect, or consequential damages resulting from the use of this information or the consequences of self-treatment.