Common Use

Isotretinoin is a potent retinoid prescribed for severe nodular or cystic acne that hasn't responded to other treatments. It reduces oil production by sebaceous glands and accelerates skin renewal. The medication also offers anti-inflammatory and antibacterial benefits. It is often recommended for acne that causes scarring or significant psychological distress.

Dosage and Direction

Isotretinoin is typically taken once or twice daily with meals to improve absorption. The dosage is determined by body weight and acne severity, usually administered over 15-20 weeks. Your doctor may adjust the dosage based on your response and tolerance. Do not share this medication or take more than prescribed.

Precautions

Before starting isotretinoin, inform your doctor if you have liver issues, high cholesterol, diabetes, or a history of depression. The drug can cause severe birth defects, so strict pregnancy prevention is essential before, during, and after treatment. Regular blood tests are needed to monitor liver function and lipid levels. Avoid waxing, dermabrasion, or laser treatments during and for several months after therapy.

Contraindications

Isotretinoin is not safe during pregnancy or for individuals allergic to retinoids or its components. It should not be used by breastfeeding women or those with uncontrolled hyperlipidemia. Avoid use in patients with liver disease or severe psychiatric disorders. Combining it with tetracycline antibiotics is discouraged due to the risk of increased intracranial pressure.

Possible Side Effects

Common side effects include dry skin, chapped lips, dry eyes, and nosebleeds. Some users report joint pain, fatigue, or increased skin sensitivity. Serious side effects may include mood changes, vision issues, liver enzyme changes, and severe birth defects. Seek immediate medical help for persistent headaches, blurred vision, or suicidal thoughts.

Drug Interaction

Isotretinoin may interact with vitamin A supplements, increasing toxicity risk. Do not combine it with tetracyclines due to the risk of pseudotumor cerebri. Avoid alcohol to prevent worsening liver side effects. Inform your doctor about all medications and supplements you are using.

Missed Dose

If you miss a dose, take it as soon as possible with food unless it's almost time for the next dose. In that case, skip the missed dose and continue your regular schedule. Do not double the dose. For best results, take the medication at the same time daily.

Overdose

Overdose symptoms may include headache, dizziness, vomiting, facial flushing, and abdominal pain. It can also increase the risk of vitamin A toxicity. Seek emergency medical help if overdose is suspected. Treatment is supportive, as there is no specific antidote.

Storage

Store isotretinoin at room temperature, away from heat, moisture, and direct light. Keep it in the original packaging and out of reach of children. Do not use after the expiration date. Dispose of unused capsules according to local pharmacy guidelines.

Disclaimer

We provide general information about medications that does not cover all directions, drug interactions, or precautions. The information on this site should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions tailored to your condition. We disclaim any reliability of this information and are not responsible for any direct, indirect, or consequential damages resulting from its use or self-treatment.