Common Use

Glycomet is an oral diabetes medication used to treat type 2 diabetes. Its active ingredient, Metformin, belongs to the biguanide class of substances. It lowers blood glucose levels by suppressing glucose metabolism in the liver, reducing glucose absorption from the gastrointestinal tract, and enhancing glucose utilization in tissues. Glycomet helps stabilize or reduce body weight and does not cause hypoglycemic reactions. It also improves blood fibrinolytic properties. This medication is prescribed for adults with type 2 diabetes, especially in cases where treatment with sulfonylurea has been ineffective, often accompanied by obesity.

Dosage and Direction

Do not use Glycomet unless prescribed by a doctor, and avoid exceeding the recommended dosage. Take it with meals unless otherwise instructed by your healthcare provider. For adults treating type 2 diabetes, Glycomet is typically taken twice daily at doses of 500 mg or once daily at 850 mg. Based on blood glucose levels, the dosage may be increased to a maximum daily dose of 2550 mg, divided into three doses.

Precautions

Glycomet may cause lactic acidosis, a life-threatening condition. Symptoms include weakness, drowsiness, slow heartbeat, cold sensations, muscle pain, abdominal pain, shortness of breath, lightheadedness, and fainting. Seek immediate medical help if these symptoms occur. Be aware of low blood sugar symptoms such as hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, and seizures. Always keep a source of sugar on hand and avoid alcohol consumption.

Contraindications

• Hypersensitivity to the drug
• Hyperglycemic coma or ketoacidosis
• Kidney or liver failure
• Heart failure or acute myocardial infarction
• Respiratory failure, dehydration, or infections
• Extensive surgery or trauma
• Alcoholism or reduced-calorie diets (less than 1000 kcal/day)
• History of lactic acidosis
• Pregnancy or breastfeeding
• Age over 60 or hard physical work (increases lactic acidosis risk)
• Contraindicated 2 days before surgery or imaging procedures (CT scans, X-rays)

Side Effects

Common yet potentially severe side effects include swelling, rapid weight gain, nausea, vomiting, gas, bloating, diarrhea, and loss of appetite. Seek emergency medical help if symptoms of lactic acidosis occur: weakness, drowsiness, slow heartbeat, cold sensations, shortness of breath, abdominal pain, muscle pain, lightheadedness, or fainting. Allergic reactions such as hives, swelling, or rash may also occur.

Drug Interactions

Cimetidine (Tagamet) increases Glycomet blood levels by affecting its metabolism. Avoid alcohol while taking Glycomet. Use caution when administering Glycomet with indirect anticoagulants or Cimetidine. Glycomet enhances Furosemide metabolism. Sulfonylurea derivatives, insulin, acarbose, MAO inhibitors, oxytetracycline, cyclophosphamide, and salicylates increase Glycomet's effects. Glycomet's hypoglycemic effect may be reduced by thyroid medications, birth control pills, hormones, Epinephrine, Glucagon, thiazide diuretics, and nicotinic acid derivatives.

Missed Dose

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose. Do not double your dose or take extra medication. Continue with your regular dosing schedule the next day.

Overdose

Symptoms of Glycomet overdose resemble low blood sugar: hunger, confusion, irritability, drowsiness, headache, weakness, tremors, sweating, fast heartbeat, and seizures. Always have a source of sugar available. If you experience these symptoms or any unusual effects, contact your doctor immediately.

Storage

Store Glycomet at room temperature between 20-25°C (68-77°F). Keep it away from moisture, heat, and sunlight. Avoid storing it in bathrooms or places accessible to children.

Disclaimer

This information provides general guidance about Glycomet and does not cover all possible directions, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider for specific instructions tailored to your condition. We disclaim responsibility for the accuracy of this information and any consequences of its use. We are not liable for any direct, indirect, or special damages resulting from the use of this information or self-treatment practices.