Gleevec (Imatinib) – Uses, Dosage, Safety Information

Common Use

Gleevec, known by its generic name imatinib, is prescribed for chronic myeloid leukemia (CML), Philadelphia chromosome‑positive acute lymphoblastic leukemia (ALL), and gastrointestinal stromal tumors (GIST). It works as a tyrosine kinase inhibitor that blocks abnormal proteins driving cancer cell growth.

Dosage and Direction

Take Gleevec orally once daily, with or without food. Swallow the tablet whole with water. Dosage varies by cancer type, patient response, and other medications. Regular blood tests and liver function monitoring are required during treatment.

Precautions

Inform your doctor of any liver or kidney disease, heart problems, low blood counts, or history of infections. Watch for swelling, unusual bleeding, or shortness of breath. Avoid pregnancy while using Gleevec, as it may cause serious birth defects.

Contraindications

Do not use Gleevec if you are allergic to imatinib or any component of the formulation. It is contraindicated during pregnancy and breastfeeding unless a healthcare professional directs otherwise.

Possible Side Effects

Common side effects include nausea, vomiting, diarrhea, fatigue, muscle cramps, and rash. Serious side effects may involve liver toxicity, low blood counts, bleeding, heart problems, or severe allergic reactions. Seek immediate medical attention if serious symptoms occur.

Drug Interactions

Gleevec may interact with other cancer medications, certain antibiotics, antifungals, anticoagulants, and drugs that affect liver enzymes. Provide your doctor with a complete list of prescription drugs, over‑the‑counter products, and supplements.

Missed Dose

If you miss a dose, take it as soon as you remember unless it is near the time of the next dose. Do not double the dose.

Overdose

Overdose can cause severe nausea, vomiting, low blood counts, liver toxicity, or heart problems. Seek emergency medical care if an overdose is suspected.

Storage

Store Gleevec at room temperature, away from moisture, heat, and light. Keep tablets in the original container and out of reach of children.

Disclaimer

This information provides a general overview of Gleevec and is not a substitute for professional medical advice. Always follow the instructions of your healthcare provider and consult them for personalized guidance.