Common Use

Endep is a tricyclic antidepressant primarily used to treat depression and obsessive-compulsive disorder (OCD). OCD is a nervous condition characterized by recurring thoughts, ideas, or repetitive behaviors driven by anxiety. Endep targets the central nervous system (CNS) to alleviate OCD symptoms by restoring the balance of natural brain chemicals like serotonin. It is also prescribed for panic attacks and chronic pain management.

Dosage and Direction

Take Endep exactly as prescribed, as the dosage and schedule depend on your condition and other factors. Follow your doctor's instructions carefully and avoid taking more or less than recommended. Do not consume grapefruit or grapefruit juice, as it affects cyclosporin levels in your blood, and limit alcohol intake. Abruptly stopping the medication can worsen your condition. It may take 2 to 3 weeks or longer to notice the medication's effects. Keep your doctor informed about your progress.

Precautions

Before starting Endep, inform your doctor or pharmacist about any drug or food allergies. Discuss any heart conditions, such as heart failure, slow heartbeat, or QT prolongation on EKG. Caution is advised for patients with seizures, glaucoma, or prostate enlargement. Endep may cause dizziness, drowsiness, or blurred vision, so avoid activities requiring alertness, like driving or operating machinery. Older adults may be more sensitive to side effects. During pregnancy, use Endep only if the benefits outweigh the risks to both mother and baby. The medication passes into breast milk, so breastfeeding is not recommended while using this drug.

Contraindications

Endep is contraindicated for patients with hypersensitivity to its components, those in the acute recovery phase of a myocardial infarction, and individuals treated with MAO inhibitors.

Possible Side Effects

Common side effects include dizziness, dry mouth, drowsiness, constipation, stomach upset, nausea, vomiting, and sweating. Anxiety symptoms may temporarily worsen when starting the medication. Serious allergic reactions are rare but require immediate medical attention. Most users do not experience severe side effects. Report any unlisted side effects to your healthcare provider or pharmacist.

Drug Interactions

Inform your doctor or pharmacist about all prescription, nonprescription, and herbal products you are using. Avoid combining Endep with:

• MAO inhibitors (e.g., Furazolidone, Isocarboxazid) to prevent high fever and convulsions.
• Anti-arrhythmic medications (e.g., Propafenone, Quinidine).
• Epinephrine, as it may cause severe high blood pressure.
• Selective Serotonin Reuptake Inhibitors (SSRIs) like Citalopram, Fluoxetine.
• Antipsychotics (e.g., Fluphenazine).
• H2-receptor antagonists (e.g., Cimetidine, Ranitidine).

Nicotine lowers blood levels of Endep, so inform your doctor if you smoke or recently quit. Avoid grapefruit or grapefruit juice during treatment.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed one and resume your regular schedule. Do not double the dose.

Overdose

Seek emergency medical attention immediately if you suspect an overdose. Symptoms include nausea, chest pain, irregular heartbeat, and light-headedness or fainting.

Storage

Store Endep at room temperature, between 68-77°F (20-25°C), away from light and moisture. Do not keep it in the bathroom. Keep all medications out of reach of children and pets.

Disclaimer

This information provides a general overview of Endep and does not cover all directions, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Specific instructions for your case must be discussed with your healthcare provider. We disclaim responsibility for the accuracy of this information or any consequences of its use, including direct, indirect, or incidental damages resulting from self-treatment.