Common Use

Efudex (fluorouracil 5%) is used to treat precancerous and cancerous skin conditions, such as actinic keratosis and superficial basal cell carcinoma. It works by interfering with the growth of abnormal skin cells.

Dosage and Direction

Apply a thin layer to the affected skin area once or twice daily as directed by your doctor. Avoid contact with eyes, mouth, and healthy skin.

Precautions

• Use sunscreen and protective clothing during treatment.
• Avoid excessive sun exposure.
• Do not apply to open wounds or mucous membranes.
• Inform your doctor if you are pregnant, breastfeeding, or have any skin infections.

Contraindications

• Not to be used in patients allergic to fluorouracil or any of the cream's components.
• Contraindicated during pregnancy and in individuals with dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.

Possible Side Effects

• Common side effects include redness, burning, itching, scaling, and skin irritation.
• Severe reactions may include blistering, ulceration, or intense inflammation.

Drug Interaction

May interact with other topical products or treatments that affect skin healing. Systemic absorption is minimal, but caution is advised when used with other chemotherapy drugs.

Missed Dose

Apply as soon as you remember. If it's close to the next dose, skip the missed one. Do not double the dose.

Overdose

Topical overdose is unlikely. In case of accidental ingestion, seek immediate medical attention.

Storage

• Store at room temperature away from light and moisture.
• Keep out of reach of children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.