Common Use

Duphaston contains dydrogesterone, a synthetic hormone similar to progesterone. This medication is used to restore hormonal balance when the body does not produce enough progesterone. It is prescribed for conditions such as sterility, abortion, premenstrual syndrome, dysmenorrhea, irregular menstruation, secondary amenorrhea, and dysfunctional uterine bleeding. Duphaston helps initiate the secretory phase in the endometrium, reducing the risk of endometrial hyperplasia and carcinogenesis caused by excess estrogen.

Dosage and Direction

The dosage and treatment plan vary depending on the condition. Always follow your doctor's instructions. For endometriosis, take 10 mg of Duphaston two to three times daily from the 5th to the 25th day of your menstrual cycle. For infertility, take 10 mg once daily from the 14th to the 25th day of your cycle. Treatment should continue for three to six consecutive cycles or as advised by your doctor. Consult your healthcare provider for specific details.

Precautions

Inform your doctor if you are pregnant or breastfeeding before taking Duphaston. Hormone replacement therapy should not begin without a thorough medical examination, including a pelvic exam. Your doctor may recommend regular mammograms as part of your treatment plan.

Contraindications

Duphaston is not suitable for individuals with hypersensitivity to its components, Dubin-Johnson syndrome (a condition involving elevated conjugated bilirubin without liver enzyme increase), or Rotor syndrome (a benign hereditary bilirubin disorder).

Side Effects

Common side effects of Duphaston include headache, nausea, dizziness, bloating, skin reactions (rash, itching), breast tenderness, and menstrual spotting between periods.

Drug Interaction

Microsomal liver enzyme inducers, such as phenobarbital, may speed up the metabolism of Duphaston and reduce its effectiveness.

Missed Dose

If you miss a dose, contact your doctor for further instructions.

Overdose

There is limited information on Duphaston overdose. Seek immediate medical attention if you suspect an overdose.

Storage

Store Duphaston at room temperature, between 20-25°C (68-77°F). Keep it away from moisture, heat, and sunlight. Avoid storing it in a bathroom or areas accessible to children.

Disclaimer

This information provides a general overview of Duphaston and does not cover all possible uses, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider for personalized advice. We are not responsible for any errors in this information or for any consequences resulting from its use.