Overview of Disulfiram

Disulfiram is a medication used to support the treatment of chronic alcoholism. It works by interfering with the metabolism of alcohol, creating unpleasant effects when alcohol is consumed. This mechanism serves as a strong deterrent, helping patients maintain sobriety.

Dosage and Direction

Disulfiram is taken orally once daily, typically in the morning. The usual dose ranges from 250 mg to 500 mg per day, depending on the patient's response. Treatment should begin at least 12 hours after the last alcoholic drink.

Precautions

Before starting disulfiram, inform your doctor if you have any of the following conditions: liver disease, heart conditions, diabetes, epilepsy, or mental health disorders. Avoid all forms of alcohol, including hidden sources like mouthwash, sauces, and certain medications. Be aware of the risks of severe reactions if alcohol is consumed during treatment.

Contraindications

Disulfiram is not suitable for individuals with severe heart disease, psychosis, or known hypersensitivity to the drug. It should not be used in patients who are currently intoxicated or without their knowledge and consent.

Possible Side Effects

Common side effects include drowsiness, headache, metallic or garlic-like taste, and skin rash. If alcohol is consumed, symptoms like flushing, nausea, vomiting, palpitations, and low blood pressure may occur. Severe reactions can include respiratory distress, cardiovascular collapse, and seizures.

Drug Interactions

Disulfiram interacts with medications such as metronidazole, isoniazid, phenytoin, and anticoagulants like warfarin. Alcohol-containing products should be strictly avoided. Inform your doctor of all medications and supplements you are using.

Missed Dose

If you miss a dose, take it as soon as you remember unless it's close to the next scheduled dose. Do not double up. Consistent daily use is crucial for the medication's effectiveness.

Overdose

Symptoms of overdose include severe drowsiness, nausea, vomiting, and neurological issues. Seek emergency medical attention immediately. Treatment is primarily supportive.

Storage

Store disulfiram at room temperature, away from heat, moisture, and light. Keep it out of reach of children and do not use expired medication.

Disclaimer

The information provided here is general and does not cover all possible directions, drug interactions, or precautions. It should not be used for self-diagnosis or self-treatment. Always consult your healthcare provider for specific guidance tailored to your condition. We are not responsible for any direct, indirect, or other damages resulting from the use of this information or self-treatment practices.