Common Use

Detrol contains tolterodine tartrate, a substance from the class of cholinergic (acetylcholine) receptor blockers. This medication is used to reduce bladder muscle spasms, overactive bladder symptoms, urge urinary incontinence, and frequency.

Dosage and Direction

Detrol is typically taken twice a day. The recommended starting dose is 2mg taken twice daily. For long-acting Detrol, begin with a 4mg daily dose. If not well tolerated, reduce the dose to 2mg. Patients with impaired liver or kidney function may require dose adjustments. Do not open, crush, or chew Detrol capsules. Swallow the tablet whole.

Precautions

Consult your doctor if you have any of the following conditions: glaucoma, kidney or liver disease, myasthenia gravis, or a personal or family history of "Long QT syndrome." Detrol may affect your ability to think, react, or concentrate. Exercise caution while driving or operating machinery.

Contraindications

Detrol is not suitable for patients with uncontrolled narrow-angle glaucoma, urinary retention, gastric retention, or a history of allergic reactions to the drug's components.

Possible Side Effects

In addition to allergic reactions such as hives, facial swelling, rash, skin eruptions, or difficulty breathing, Detrol may cause chest pain, fast or uneven heart rate, confusion, painful or difficult urination, hallucinations, or reduced urination.

Drug Interactions

Inform your doctor about all prescribed and over-the-counter medications you are taking. Specific drugs that may interfere with the liver's elimination of tolterodine include:

• Cyclosporine (Gengraf, Neoral, Sandimmune)
• Clarithromycin (Biaxin)
• Azithromycin (Zithromax)
• Erythromycin
• Telithromycin (Ketek)
• Pentamidine (NebuPent, Pentam)
• Sparfloxacin (Zagam)
• Itraconazole (Sporanox)
• Ketoconazole (Nizoral)
• Miconazole (Monistat, Micatin)
• Arsenic trioxide (Trisenox)
• Chloroquine (Arelan) or halofantrine (Halfan)
• Levomethadyl (Orlaam)
• Methadone (Dolophine, Methadose)
• Vinblastine (Velban)
• Psychiatric medications such as chlorpromazine (Thorazine), mesoridazine (Serentil), pimozide (Orap), haloperidol (Haldol), or thioridazine (Mellaril)
• Heart rhythm medications such as disopyramide (Norpace), procainamide (Procan, Pronestyl), amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), sotalol (Betapace), quinidine (Cardioquin, Quinaglute)

Missed Dose

Do not take a double dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Overdose

Symptoms of overdose may include blurred vision, dry mouth, and a fast heartbeat.

Storage

Store Detrol at room temperature between 15-30°C (59-86°F), away from moisture and heat.

Disclaimer

This information provides a general overview and does not cover all directions, possible drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider or doctor for specific instructions. We disclaim any reliability of this information and are not responsible for any direct, indirect, or consequential damages resulting from its use or self-treatment.