Common Use

Danocrine's active component is danazol, a synthetic steroid that influences the ovaries and pituitary gland to inhibit the release of specific hormones. This medication is prescribed for treating endometriosis and fibrocystic breast disease. It is also used to prevent angioedema attacks in individuals with an inherited form of the disorder.

Dosage and Directions

Take Danazol exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration. Treatment may need to start during a menstrual period. Adjustments may be necessary during periods of unusual stress, such as serious illness, fever, infection, surgery, or medical emergencies. Inform any treating doctor that you are using Danazol, as it may affect medical test results.

Precautions

Consult your doctor if you have:

• Severe heart, kidney, or liver disease
• Porphyria or abnormal vaginal bleeding
• Pregnancy or a history of stroke or blood clot
• Breast cancer, high cholesterol, or triglycerides
• Coronary artery disease, heart disease, or congestive heart failure
• Seizure disorder or migraine headaches

Contraindications

Do not use Danazol if you have:

• An allergy to danazol
• Severe heart, liver, or kidney problems
• Porphyria or abnormal vaginal bleeding
• Pregnancy or breast-feeding

Danazol can cause birth defects, so use effective birth control methods.

Possible Side Effects

Serious side effects include:

• Sudden numbness, weakness, confusion, vision, speech, or balance problems
• Chest pain, sudden cough, wheezing, rapid breathing, or fast heart rate
• Swelling, rapid weight gain, or shortness of breath
• Headache, ringing in the ears, dizziness, nausea, vision problems, or pain behind the eyes
• Stomach pain, loss of appetite, dark urine, or jaundice

Less serious side effects include:

• Acne, skin problems, increased hair growth, or hair loss
• Weight gain, breast changes, or deepened voice
• Nervousness, increased sweating, or warmth/tingling under the skin
• Changes in menstrual periods or vaginal dryness, discomfort, or itching

Drug Interaction

Inform your doctor if you are taking blood thinners (e.g., warfarin) or carbamazepine before starting Danocrine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue as scheduled. Do not take extra medicine to compensate.

Overdose

Seek emergency medical assistance if you overdose. Overdose symptoms include weight gain, increased acne or facial hair growth, menstrual problems, or breast changes.

Storage

Store Danazol between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Keep it out of reach of children and pets. Do not store in the bathroom.

Disclaimer

This information provides a general overview and does not cover all directions, drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific guidelines. We disclaim responsibility for any errors, omissions, or damages resulting from the use of this information or consequences of self-treatment.