CommonUse

Combigan eye drops are used to lower elevated intraocular pressure in patients with open‑angle glaucoma or ocular hypertension. The formulation combines Brimonidine, an alpha‑agonist, and Timolol, a beta‑blocker, to reduce fluid production and improve fluid drainage inside the eye.

Dosage and Direction

Instill one drop in the affected eye(s) twice daily, approximately 12 hours apart. Follow the prescribed schedule exactly and avoid touching the dropper tip to any surface to prevent contamination.

1. Wash hands thoroughly before each use.
2. Tilt the head back and pull down the lower eyelid.
3. Apply one drop into the eye without letting the dropper touch the eye.
4. Close the eye gently for a few minutes.
5. Repeat the process for the second dose, maintaining about 12 hours between applications.

Precautions

Inform your doctor if you have heart conditions, asthma, diabetes, or circulation problems. Combigan may cause drowsiness or blurred vision; exercise caution when driving or operating machinery.

• Avoid using other eye medications unless directed by a healthcare provider.
• Do not wear contact lenses while the drops are in use without doctor approval.

Contraindications

Do not use Combigan if you have asthma, severe chronic obstructive pulmonary disease (COPD), an abnormally slow heart rate, or heart block. Also avoid use if you are allergic to Brimonidine, Timolol, or other beta‑blockers.

Possible Side Effects

Common side effects may include eye discomfort, redness, dry mouth, and fatigue. Serious side effects can involve slow heart rate, difficulty breathing, or severe allergic reactions. Seek medical attention if any serious symptoms occur.

Drug Interactions

Combigan may interact with antidepressants (especially MAO inhibitors), blood pressure medications, and other beta‑blockers. Provide your physician with a complete list of all medications you are currently taking.

Missed Dose

If you remember a missed dose, apply it as soon as you recall. If the time for the next scheduled dose is near, skip the missed dose - do not double up to make up for it.

Overdose

Signs of overdose may include low blood pressure, dizziness, or respiratory problems, particularly in children. If an overdose is suspected, contact emergency medical services immediately.

Storage

Store Combigan drops at room temperature, away from heat and direct light. Keep the bottle tightly closed and out of the reach of children.

Disclaimer

This information provides general guidance about medications and is not a substitute for professional medical advice. Always follow the specific instructions given by your healthcare provider. The content presented here is for educational purposes only and should not be used for self‑diagnosis or self‑treatment.