Common Use

Chloroquine is an aminoquinoline used to treat or prevent malaria infections and certain types of parasitic infections. It works by killing malaria parasites, most likely by damaging their DNA (genetic material).

Dosage and Directions

Chloroquine is taken by mouth with a glass of water or food. Dosage varies depending on the type of infection:

• Malaria: For Adults: 500 mg on the same day each week; For Children: 5 mg (calculated as base) per kg of body weight. Alternatively, 10 mg base/kg may be taken in two divided doses, six hours apart.
• Treatment of Acute Attack: For Adults: 1 g followed by an additional 500 mg after six to eight hours, and a single dose of 500 mg on each of two consecutive days.

Note: This information is for review purposes only. Always consult your doctor before using Chloroquine to ensure the best results.

Precautions

Long-term use of Chloroquine may lead to symptoms such as blood problems or muscle weakness. Contact your doctor immediately if you experience changes in vision, worsening symptoms, or if symptoms do not improve within a few days. Avoid activities like driving or operating machinery if your vision is impaired.

Contraindications

Chloroquine should not be used by individuals with hypersensitivity, liver or kidney disorders, cardiac muscle impairments, blood or nervous system illnesses, retina or cornea issues, diabetes, or chronic alcoholism. Do not use if allergic to Chloroquine or its ingredients, or if you have certain visual problems (unless the benefits outweigh the risks in malaria treatment).

Possible Side Effects

Common side effects include appetite loss, clumsiness, diarrhea, dizziness, nausea, stomach cramps, and vomiting. Serious side effects may include severe allergic reactions, bizarre behavior, vision problems, hair loss, hearing loss, seizures, or unusual weakness. Discontinue use and consult your doctor immediately if you experience any of these.

Drug Interactions

Chloroquine may interact with medications such as ampicillin, antacids containing magnesium, cimetidine, cyclosporine, and kaolin. Consult your doctor to manage these interactions effectively.

Missed Dose

If you miss a dose, take it as soon as you remember. Do not take a double dose if it's almost time for your next dose. Resume your regular dosing schedule the next day.

Overdose

Symptoms of overdose include headache, drowsiness, nausea, vomiting, seizures, difficulty breathing, unconsciousness, convulsions, and coma. Death due to respiratory distress may occur within 2 hours of intake. Seek immediate medical attention if overdose is suspected.

Storage

Store Chloroquine at room temperature (59-77°F or 15-25°C) away from light, moisture, children, and pets. Do not use after the expiration date.

Disclaimer

This information provides general details about Chloroquine and does not cover all directions, drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions. We disclaim responsibility for any errors or damages resulting from the use of this information.