Common use

Cefixime is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is effective against:

• Respiratory tract infections
• Urinary tract infections
• Ear infections (otitis media)
• Throat infections (tonsillitis/pharyngitis)
• Gonorrhea

Cefixime works by inhibiting bacterial cell wall synthesis, which leads to the destruction of the bacteria. It is not effective against viral infections like the common cold or flu.

Dosage and direction

• Typical adult dose: 200-400 mg per day
• May be taken as a single dose or divided into two doses every 12 hours
• Available as tablets, capsules, or oral suspension
• Can be taken with or without food

For liquid form: Shake well before use and measure with proper dosing device. Always complete the full prescribed course, even if symptoms improve early.

Precautions

Before using cefixime, inform your doctor if you have:

• History of penicillin or cephalosporin allergy
• Kidney disease
• Gastrointestinal problems (such as colitis)

Use with caution in elderly patients and those with renal impairment. Long-term use may lead to secondary infections like yeast or fungal overgrowth. Always follow your healthcare provider's instructions.

Contraindications

Cefixime should not be used in:

• Patients with known hypersensitivity to cefixime or other cephalosporins
• Those with severe allergy history to penicillin-related antibiotics
• Patients with porphyria

Pediatric use requires physician guidance based on body weight.

Possible side effects

Common side effects:

• Diarrhea
• Nausea
• Abdominal pain
• Gas

Less common reactions:

• Rash
• Headache
• Dizziness

Seek immediate medical attention for:

• Signs of allergic reaction
• Severe diarrhea (possible Clostridium difficile infection)
• Swelling or difficulty breathing
• Liver problems

Drug interactions

• Warfarin: increased bleeding risk
• Live bacterial vaccines: reduced effectiveness
• Probenecid: may increase cefixime levels

Always inform your doctor about all medications and supplements you're taking.

Missed dose

If you miss a dose:

• Take it as soon as you remember
• If near next dose time, skip the missed dose
• Never double doses

Maintaining the prescribed schedule ensures effectiveness and prevents antibiotic resistance.

Overdose

Symptoms may include:

• Nausea
• Vomiting
• Diarrhea
• Seizures (in severe cases)

Seek emergency medical help for suspected overdose. Treatment includes symptom management, with possible dialysis for renal failure patients.

Storage

• Tablets/capsules: Store at 20°C to 25°C (68°F to 77°F), away from light/moisture
• Suspension: Refrigerate, discard after 14 days
• Do not freeze suspension
• Keep all medications out of children's reach

Disclaimer

This information provides general guidelines about cefixime and does not cover all possible uses, interactions, or precautions. Never use this information for self-diagnosis or self-treatment. Always consult with your healthcare provider for personalized medical advice. We cannot guarantee the absolute accuracy of this information and disclaim responsibility for any consequences resulting from its use.