Common Use

Brand Cialis, developed by the pharmaceutical company LILLY, contains Tadalafil as its main component. Cialis is a highly effective, reversible, and selective inhibitor of phosphodiesterase type 5 (PDE 5), which is specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation triggers the release of nitric oxide, Cialis inhibits PDE 5, leading to increased cGMP levels in the cavernous body of the penis. This process relaxes arterial smooth muscles, enhancing blood flow to the penile tissues and facilitating erections. Cialis only works in the presence of sexual stimulation. It improves erections, enabling successful sexual intercourse, and its effects last for up to 36 hours. The drug can take effect in as little as 16 minutes after consumption if sexual arousal is present.

Dosage and Direction

The recommended dose of Cialis is 20 mg, which should be taken at least 16 minutes before sexual activity. The effects of the medication can last up to 36 hours. Cialis should be taken once daily, and the recommended dose should not be exceeded.

Precautions

It is advisable to avoid consuming Cialis with grapefruit juice, alcoholic beverages, or tobacco. Combining Cialis with tobacco smoking may increase the risk of NAION (sudden optic nerve-related vision loss). Consult your doctor before using Cialis if you have:

• Abnormal penis conditions, including curvature or birth defects
• History of coronary artery disease, arrhythmia, angina, heart attack, or heart failure
• Hypotension or hypertension
• Bleeding disorders, stomach ulcers, diabetes, or hyperlipidemia (excess lipids in the blood)
• Sickle-cell anemia
• Liver or kidney failure

Contraindications

Cialis is contraindicated in patients using organic nitrates, either regularly or intermittently, as it can amplify the hypotensive effects of nitrates.

Possible Side Effects

Common side effects of Cialis include:

• Facial flushing (reddening)
• Headaches
• Stomach upset
• Diarrhea
• Flu-like symptoms
• Nausea

Rare side effects may include:

• Low blood pressure
• Blurred vision or changes in color vision
• Abnormal ejaculation
• Prolonged erections or priapism (painful erections lasting more than 6 hours)

If an erection lasts longer than 4 hours, seek immediate medical attention to prevent permanent damage to the penis. Cialis may also exacerbate heart problems in patients with pre-existing heart conditions.

Drug Interactions

Cialis should not be taken with medications containing organic nitrates, as this combination can cause severe hypotension. Avoid using Cialis with:

• Erythrityl Tetranitrate
• Isosorbide Dinitrate
• Isosorbide Mononitrate
• Nitroglycerin
• Pentaerythritol Tetranitrate

Medications such as erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan), and ritonavir (Norvir) can increase Cialis levels and toxicity. Inform your doctor if you are taking any of the following, as your Cialis dose may need adjustment:

• Atazanavir
• Bunazosin
• Clarithromycin
• Doxazosin
• Indinavir
• Itraconazole
• Ketoconazole
• Moxisylyte
• Nefazodone
• Nelfinavir
• Phenoxybenzamine
• Phentolamine
• Prazosin
• Saquinavir
• Telithromycin
• Terazosin
• Trimazosin
• Urapidil

Missed Dose

There is no need to worry about a missed dose of Cialis when used for erectile dysfunction, as it is taken on an as-needed basis.

Overdose

An overdose of Cialis may result in symptoms similar to its side effects. Seek immediate medical attention if you suspect you have taken too much of this medication.

Storage

Store Cialis at room temperature in a tightly sealed container, away from moisture, sunlight, children, and pets.

Disclaimer

The information provided here is general and does not cover all directions, possible drug interactions, or precautions. It should not be used for self-treatment or self-diagnosis. Always consult your healthcare provider or doctor for specific instructions tailored to your condition. We disclaim any responsibility for the reliability of this information or any errors it may contain. We are not liable for any direct, indirect, special, or other damages resulting from the use of this information or the consequences of self-treatment.