Common Use

Bactrim contains two active ingredients: sulfamethoxazole and trimethoprim. Sulfamethoxazole inhibits the synthesis of dihydrofolic acid, a substance essential for human and bacterial metabolism. Trimethoprim blocks the next stage of the biochemical cycle, preventing the formation of tetrahydrofolic acid, a process unique to microorganisms. This combination makes Bactrim effective against infections caused by streptococci, staphylococci, pneumococci, bacillus dysentery, typhoid fever, E. coli, and Proteus. However, it is ineffective against Mycobacterium tuberculosis, spirochetes, and Pseudomonas aeruginosa. Bactrim is commonly used to treat pneumonia and infections of the respiratory, gastrointestinal, and urogenital systems, including post-surgical bacterial infections.

Dosage and Directions

Bactrim can be taken two to three times daily, with or without food. The dosage varies depending on the type and severity of the infection. Always take the medication with a full glass of water. Patients with severe kidney impairment may require adjusted dosages.

Precautions

• Avoid prolonged exposure to sunlight or tanning beds while using Bactrim.
• Antibiotics may cause diarrhea. Inform your doctor if it occurs, as it could indicate another infection.
• Notify your healthcare provider if you have asthma or severe kidney or liver disorders.

Contraindications

Do not use Bactrim if you are allergic to its components, pregnant, breastfeeding, or have anemia caused by folic acid deficiency. This medication is also contraindicated in premature babies and newborns.

Possible Side Effects

Seek immediate medical attention if you experience signs of an allergic reaction, such as hives, difficulty breathing, swelling of the face, lips, tongue, or throat. Other serious side effects include fever, sore throat, headache with severe blistering, pale skin, easy bruising or bleeding, watery or bloody diarrhea, hallucinations, slow heart rate, weak pulse, nausea, stomach pain, or reduced urination.

Drug Interactions

Bactrim should not be co-administered with dofetilide or methenamine. It may alter the effects of anti-diabetic medications, blood thinners, cyclosporine, digoxin, potassium-increasing drugs, live vaccines, tricyclic antidepressants, and certain diuretics. Inform your doctor about all prescription and nonprescription or herbal products you are using.

Missed Dose

If you miss a dose, do not double the next dose. Skip the missed dose and continue with your regular schedule.

Overdose

Symptoms of overdose may include dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of the skin or eyes, blood in the urine, or fainting. Seek immediate medical help if you suspect an overdose.

Storage

Store Bactrim at room temperature, between 59-77°F (15-25°C), away from light, moisture, children, and pets.

Disclaimer

This information provides a general overview of Bactrim and does not include all possible directions, drug interactions, or precautions. It is not intended for self-diagnosis or self-treatment. Always consult your healthcare provider or doctor for personalized advice. We do not guarantee the accuracy or reliability of this information and are not liable for any direct, indirect, or consequential damages resulting from its use or self-treatment.