Common Use

Avapro is an antihypertensive drug and an angiotensin II receptor antagonist. It specifically and irreversibly blocks angiotensin receptors, reducing the biological effects of angiotensin II. These effects include vasoconstriction, stimulation of aldosterone excretion, and activation of the sympathetic nervous system. As a result, arterial pressure decreases, reducing the heart's workload. Avapro does not affect the concentration of triglycerides, cholesterol, glucose, uric acid in blood plasma, or uric acid excretion in urine.

Dosage and Direction

The initial dose of Avapro is 150 mg, which can be increased to 300 mg if necessary. In certain cases, such as a low-chloride diet, treatment with specific diuretics, or other conditions, a smaller initial dose may be required. Avapro should be taken once daily, preferably at the same time each day.

Precautions

Use Avapro with caution in patients with kidney or liver failure, congestive heart failure, or after severe vomiting or diarrhea. Caution is also advised when using this drug alongside potassium-sparing diuretics or potassium-containing medications. Avapro can cause serious harm to an unborn baby, including death, if used during the last six months of pregnancy.

Contraindications

Avapro is contraindicated during pregnancy, in infancy, and in individuals with hypersensitivity to the drug.

Possible Side Effects

Common side effects include diarrhea, abdominal pain, or heartburn. Seek medical attention if you experience an allergic reaction, such as fever, difficulty breathing, or hives. Avapro may cause a condition leading to the breakdown of skeletal muscle tissue and subsequent kidney failure. Contact your doctor immediately if you experience muscle pain, tenderness, weakness, vomiting, dark-colored urine, or difficulty urinating.

Drug Interaction

No significant drug interactions have been reported for Avapro. However, when taken with potassium-sparing diuretics, potassium levels in the blood plasma may increase.

Missed Dose

Do not take a double dose if you miss one. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Overdose

Seek immediate medical help in case of overdose. Symptoms may include a fast or slow heartbeat and dizziness.

Storage

Store Avapro tablets at room temperature, between 15-30°C (59-86°F).

Disclaimer

The information provided here is general and does not cover all directions, possible drug interactions, or precautions. It is not intended for self-treatment or self-diagnosis. Always consult your healthcare provider for specific instructions tailored to your condition. We do not guarantee the accuracy or reliability of this information and are not responsible for any direct, indirect, or consequential damages resulting from its use or self-treatment.