Common Use

This medication belongs to the group of calcium channel blockers. Amlodipine selectively blocks channels of L-type (one of six types of channels in tissues) located in a vascular wall, myocard and in particular in cells of conducting and contractile systems of myocardium.

By blocking Ca+ ions transfer through membrane, Amlodipine decreases tone of vessels and arterial pressure. The medication is used to treat:

• Hypertension
• Ischemic heart disease
• Angina

Dosage and Direction

Do not take this drug if it was not prescribed to you. Always follow your doctor's directions.

• Can be taken with or without food
• Metabolized in liver - use with caution in patients with liver failure

Precautions

• Avoid alcohol consumption
• Inform your doctor if you have:
• Congestive heart failure
• Liver disease

Contraindications

• Individual hypersensitivity
• Arterial hypotension
• Cardiogenic shock
• Pregnancy
• Breastfeeding

Use with caution in patients with:

• Chronic heart failure
• Diabetes
• Lipid metabolism disorders
• Liver failure
• Patients younger than 18 years

Possible Side Effects

• Common: Edema of lower extremities and headache
• Contact your doctor if you experience:
• Swelling in hands, ankles, or feet
• Chest pain
• Slow, fast, or pounding heartbeats
• Easy bruising or bleeding
• Unusual weakness
• Numbness, burning, pain, or tingly feeling
• Jaundice

Drug Interactions

• Medications containing Ca2+ may decrease Amlodipine effect
• NSAIDs and estrogens may decrease effectiveness
• Diuretics may increase activity
• Concomitant use with lithium may increase lithium toxicity

Missed Dose

• Take missed dose as soon as remembered, unless near next scheduled dose
• Do not double dose to compensate

Overdose

Seek immediate medical help if experiencing:

• Tingly feeling
• Severe dizziness
• Fainting

Storage

• Store at room temperature (15-30°C / 59-86°F)
• Keep in light-resistant container
• Protect from moisture

Disclaimer

This information provides general guidelines only and does not cover all possible directions, drug interactions, or precautions. The content should not be used for self-treatment or self-diagnosis.

Always consult your healthcare provider for specific instructions regarding your treatment. We cannot guarantee the completeness or accuracy of this information and disclaim responsibility for any consequences of its use.