Common Use

Aciphex is an antiulcer medication that inhibits the proton pump (PPIs), blocking stomach acid production. It works by biochemically blocking the (H+,K+)-ATPase enzyme system, which stops the final stage of hydrochloric acid production. The antisecretory effect begins within one hour after taking Aciphex orally, reaching its peak in 2-4 hours.

This medication is prescribed to treat:

• Stomach ulcers
• Zollinger-Ellison syndrome
• Gastroesophageal reflux disease (GERD)
• Helicobacter pylori infections in patients with stomach ulcers or chronic gastritis

Dosage and Directions

Your doctor will determine the correct dosage based on your condition. General guidelines include:

• Acute duodenal ulcer: 1 tablet (20 mg) taken once daily in the morning for 4-6 weeks.
• H. pylori infection: Aciphex may only be needed for one week.

Follow all medical recommendations and never exceed the prescribed dose. Swallow tablets whole, do not crush, split, or chew them. Aciphex can be taken with or without food, but always with a full glass of water, as food has minimal impact on absorption.

Precautions

Consult your doctor before using Aciphex if you have:

• Severe liver disease
• Stomach cancer

Aciphex is not recommended for children. While it is not expected to harm an unborn baby, inform your doctor if you are pregnant or breastfeeding. For certain conditions, Aciphex may be prescribed with antibiotics, take all medications as directed for maximum effectiveness.

Contraindications

Do not use Aciphex if you:

• Are pregnant or breastfeeding
• Have a hypersensitivity to Aciphex or substituted benzimidazoles like omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), or esomeprazole (Nexium)

Possible Side Effects

Common side effects may include:

• Headache or dizziness
• Dry mouth, upset stomach, or diarrhea
• Constipation, insomnia, or nervousness
• Rash or itching

Seek immediate medical help if you experience severe allergic reactions (hives, swelling of the tongue/face) or persistent side effects.

Drug Interactions

Aciphex may interact with medications that depend on stomach acidity for absorption. Examples include:

• Reduced effectiveness: Ketoconazole (Nizoral)
• Increased toxicity risk: Digoxin (Lanoxin)

Always inform your doctor about other medications you are taking.

Missed Dose

If you miss a dose, take it as soon as you remember, unless it's close to your next scheduled dose. Never double dose to compensate for a missed one.

Overdose

Symptoms of Aciphex overdose are unknown. Seek emergency medical attention if you suspect an overdose.

Storage

Store Aciphex at room temperature (59-77°F / 15-25°C) away from light, moisture, children, and pets.

Disclaimer

This information is for general purposes only and does not cover all possible uses, interactions, or precautions. Never self-diagnose or self-medicate. Always consult your healthcare provider for personalized advice. We do not guarantee the accuracy or completeness of this information and are not liable for any consequences of its use.